If you notice any other effects, check with your healthcare professional.Call your doctor for medical advice about side effects. All rights reserved.See how we're providing safe in-person care and virtual visits,Review the latest COVID-19 resources and research advancements,Mayo Clinic College of Medicine and Science,Mayo Clinic Graduate School of Biomedical Sciences,Mayo Clinic School of Continuous Professional Development,Mayo Clinic School of Graduate Medical Education,FREE book offer – Mayo Clinic Health Letter,fast, pounding, or irregular heartbeat or pulse,holding false beliefs that cannot be changed by fact,irregular, fast or slow, or shallow breathing,large, hive-like swelling on face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs,peculiar postures or movements, mannerisms or grimacing,seeing, hearing, or feeling things that are not there,sores, ulcers, or white spots on lips or in mouth,unusual excitement, nervousness, or restlessness,dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly,pupils of eyes large and not moving or responding to light,redness of the face, neck, arms and occasionally, upper chest,unsteadiness, trembling, or other problems with muscle control or coordination,blistering, crusting, irritation, itching, or reddening of skin,continuing ringing or buzzing or other unexplained noise in ears,increased sensitivity of skin to sunlight. If you take this medicine (promethazine tablets) on a regular basis, take a missed dose as soon as you think about it. Keep out of direct or strong sunlight and follow.If you're over 65, you're more likely to experience side effects such as:Children are more likely to experience side effects such as feeling restless or excited.Call your doctor straight away if you have:In rare cases, it's possible to have a serious allergic reaction.You could be having a serious allergic reaction and may need immediate treatment in hospital.These aren't all the side effects of promethazine. These include.Most people prefer to take a non-drowsy antihistamine as it's less likely to interfere with their everyday routine.You might choose to take a drowsy antihistamine, however, if you're having problems falling asleep, or if symptoms like itching or coughing are keeping you awake.There isn't enough information available to say whether one antihistamine is better than another for treating allergies.You may need to try a few different medicines to find what works best for you. Although not all of these side effects may occur, if they do occur they may need medical attention.Stop taking promethazine and get emergency help immediately if any of the following effects occur:Some side effects of promethazine may occur that usually,Check with your health care professional if any of the following side effects.The most commonly reported side effect include drowsiness, dizziness, and restlessness.1.

Promethazine can cause side effects that may impair your thinking or reactions. Promethazine (Oral Route) Print. The medicine should work for around 4 to 6 hours.You should only take promethazine for a short time, unless your doctor says it's OK for you to take it for longer.Speak to your pharmacist or doctor before taking promethazine for longer than the medicine leaflet recommends.Ask them for advice if you're unsure how long you should take it for.It's unlikely that you'll get addicted to promethazine. It's classed as a drowsy (sedating) antihistamine.When you come into contact with something you're.Promethazine blocks the effects of histamine in your brain and this reduces symptoms.It enters the brain in large quantities and this can make you feel drowsy.Promethazine also blocks the effects of a chemical called dopamine, and this stops you feeling sick.Promethazine blocks the effects of a natural chemical called acetylcholine.This can help dry up a cough or runny nose, but can also cause side effects such as a dry mouth and dry nose.Although some people find them helpful, they're not usually recommended.This is because there's little evidence that they're any more effective than simple home remedies and they're not suitable for everyone.Promethazine will start to make you feel sleepy around 20 minutes after you take it and may work for up to 12 hours.If you're taking it for a cough or cold, allergies or nausea, your symptoms should start to improve within 20 minutes.

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